Researchers report fastest purification of astatine-211 needed for targeted cancer therapy

Astatine-211 recovery from bismuth metal using a chromatography system. Unlike bismuth, astatine-211 forms chemical bonds with ketones.
In a recent study, Texas A&M University researchers have described a new process to purify astatine-211, a promising radioactive isotope for targeted cancer treatment. Unlike other elaborate purification methods, their technique can extract astatine-211 from bismuth in minutes rather than hours, which can greatly reduce the time between production and delivery to the patient.
“Astatine-211 is currently under evaluation as a cancer therapeutic in clinical trials. But the problem is that the supply chain for this element is very limited because only a few places worldwide can make it,” said Jonathan Burns, research scientist in the Texas A&M Engineering Experiment Station’s Nuclear Engineering and Science Center. “Texas A&M University is one of a handful of places in the world that can make astatine-211, and we have delineated a rapid astatine-211 separation process that increases the usable quantity of this isotope for research and therapeutic purposes.”
The researchers added that this separation method will bring Texas A&M one step closer to being able to provide astatine-211 for distribution through the Department of Energy’s Isotope Program’s National Isotope Development Center as part of the University Isotope Network.
Details on the chemical reaction to purify astatine-211 are in the journal Separation and Purification Technology.








 The Environmental Protection Agency has awarded three contracts for cleanup efforts at more than 50 abandoned uranium mine sites in and around the Navajo Nation in the southwestern United States. The Navaho Area Abandoned Mine Remedial Construction and Services Contracts, worth up to $220 million over the next five years, were awarded to the Red Rock Remediation Joint Venture, Environmental Quality Management, and Arrowhead Contracting, the agency announced on February 11.
The Environmental Protection Agency has awarded three contracts for cleanup efforts at more than 50 abandoned uranium mine sites in and around the Navajo Nation in the southwestern United States. The Navaho Area Abandoned Mine Remedial Construction and Services Contracts, worth up to $220 million over the next five years, were awarded to the Red Rock Remediation Joint Venture, Environmental Quality Management, and Arrowhead Contracting, the agency announced on February 11.
 Maybe everything really is bigger in Texas, but that’s not necessarily a good thing. The brutal winter storm that hit much of the country earlier this week struck the Lone Star State with particular severity, leaving the power grid in shambles and millions of Texas residents without power, in many instances for days. On Tuesday, at the height of the power crisis, more than 4.4 million utility customers were without access to electricity, according to
Maybe everything really is bigger in Texas, but that’s not necessarily a good thing. The brutal winter storm that hit much of the country earlier this week struck the Lone Star State with particular severity, leaving the power grid in shambles and millions of Texas residents without power, in many instances for days. On Tuesday, at the height of the power crisis, more than 4.4 million utility customers were without access to electricity, according to 
 Coordinated federal and private industry investments made now could yield an operational fusion pilot plant in the 2035–2040 time frame, according to
Coordinated federal and private industry investments made now could yield an operational fusion pilot plant in the 2035–2040 time frame, according to 