Isotopes & Radiation

Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.

Kathryn Higley

For nearly a century, the National Council on Radiation Protection and Measurements has served as the United States’ leading authority on radiation protection. Established in 1929 as the Advisory Committee on X-ray and Radium Protection, the NCRP was created in response to growing concerns about the health risks of radiation exposure following the discoveries of X-rays and radioactivity.

It was formally chartered by Congress in 1964 through Public Law 88-376, also known as the National Council on Radiation Protection and Measurements Charter Act. The NCRP has provided science-­based guidance for the public, workers, and the environment. Its work spans a wide range of topics, including protecting patients and workers in medical, industrial, and environmental settings; supporting emergency preparedness; developing risk models for low-dose exposures; guiding safe practices for new technologies such as advanced nuclear reactors; and providing information on wireless communication devices.

Radiation protection specialists agree that clear communication of radiation risks remains a vexing challenge that cannot be solved solely by finding new ways to convey technical information.

Earlier this year, an article in Nuclear News described a new radiation risk communication tool, known as the Radiation Index, or, RAIN (“Let it RAIN: A new approach to radiation communication,” NN, Jan. 2025, p. 36). The authors of the article created the RAIN scale to improve radiation risk communication to the general public who are not well-versed in important aspects of radiation exposures, including radiation dose quantities, units, and values; associated health consequences; and the benefits derived from radiation exposures.

In commercial nuclear power, there has always been a deliberate tension between the regulator and the utility owner. The regulator fundamentally exists to protect the worker, and the utility, to make a profit. It is a win-win balance.

From the U.S. nuclear industry has emerged a brilliantly successful occupational nuclear safety record—largely the result of an ALARA (as low as reasonably achievable) process that has driven exposure rates down to what only a decade ago would have been considered unthinkable. In the U.S. nuclear industry, the system has accomplished an excellent, nearly seamless process that succeeds to the benefit of both employee and utility owner.

Craig Piercy
cpiercy@ans.org

So, President Trump has just kicked the low-dose radiation hornets’ nest.

Specifically, his recently signed executive order “Ordering the Reform of the Nuclear Regulatory Commission” calls for the NRC to “reconsider reliance” on the linear no-threshold (LNT) theory and the ALARA (as low as reasonably achievable) standard for radiation protection.

This directive will certainly reignite a vociferous debate within the radiation research community over the continued efficacy of using LNT as the basis for protecting the public and the environment, a community that has been wracked with controversy on this matter for the last few years.

I must admit that whenever the low-dose issue comes up, my first thoughts always go to Sayre’s Law.

The day before the 2025 ANS Annual Conference officially began in Chicago, the air was abuzz with the crackle of Geiger counters at Argonne National Laboratory in neighboring Lemont, Ill., where about 100 visitors from across the country attended an outreach and education event hosted by the American Nuclear Society.

There is a critical knowledge gap regarding the health consequences of exposure to radiation received gradually over time. While there is a plethora of studies on the risks of adverse outcomes from both acute and high-dose exposures, including the landmark study of atomic bomb survivors, these are not characteristic of the chronic exposure to low-dose radiation encountered in occupational and public settings. In addition, smaller cohorts have limited numbers leading to reduced statistical power.

Workers with Oak Ridge Office of Environmental Management contractor Isotek have surpassed a significant milestone in the supply of medical radioisotopes, extracting more than 15 grams of rare thorium-229 through the Department of Energy’s Thorium Express Project.

Framatome announced that it has inaugurated a new workshop dedicated to the fabrication of fuel for research reactors and targets for medical isotopes at the company’s Romans-sur-Isère site in France. The workshops are part of Framatome’s CERCA division, which manufactures fuel and irradiation targets for research reactors.

Despite its significant benefits, the public perception of radiation is generally negative due to its inherent nature: it is ubiquitous yet cannot be seen, heard, smelled, or touched—as if it were a ghost roaming around uncensored. The public is frightened of this seemingly creepy phantom they cannot detect with their senses. This unfounded fear has hampered the progress of the nuclear industry and radiation professions.

Two research scientists from Japan’s Kyoto University and Kochi University of Technology visited the West Valley Demonstration Project in western New York state earlier this fall to test their novel radiation detectors, the Department of Energy’s Office of Environmental Management announced on November 19.

Oklo Inc. has that it has signed a letter of intent to acquire Atomic Alchemy Inc., a U.S.-based radioisotope production company. The two companies announced a strategic partnership earlier this year.

Workers recently completed an 18-month project replacing 11 hot cell windows at the 222-S Laboratory at the Department of Energy’s Hanford Site in Washington state. Hanford contractor Navarro-ATL manages the lab.

Key developments, emerging trends, challenges, and innovations in the field of health physics are the topic of a recently published article in Health Physics Journal. The authors of “The Future of Health Physics: Trends, Challenges, and Innovation,” Lekhnath Ghimire and Edward Waller, write that they hope to “foster dialogue and collaboration for the unpredictable yet exciting journey ahead” in health physics.

TerraPower Isotopes, a subsidiary of Bellevue, Wash.–based TerraPower, announced it is now producing actinium-225 at commercial scale, making the medical isotope available to the pharmaceutical industry through weekly production runs. As a result, TerraPower Isotopes said its actinium, after further manufacturing, is now used in multiple drug developers’ radiopharmaceuticals in human clinical trials across the globe.

Kasparov

More than 80 percent of the territory that has been surveyed around the Chernobyl nuclear power plant “can be returned to agricultural production,” said Valery Kashparov, director of the Ukrainian Institute of Agricultural Radiology (UIAR) of the National University of Life and Environmental Sciences of Ukraine.

Kashparov’s team of researchers reported in a recent article in New Scientist the results of its radiation surveys of areas around the site of the 1986 nuclear power plant accident. The group concluded that radiation measurements on much of the land are now below levels regarded as unsafe by Ukrainian regulators.

Decades of research: Kashparov, who has been with the UIAR since 1998, has spent the past 37 years conducting research related to Chernobyl, focusing on the physical-chemical and nuclear-physical properties of radioactive fallout in the area.

Kilindini Harbor in Mombasa, Kenya, is East Africa’s largest international seaport. But rapid development of the Kenyan coastal zone is changing sediment distribution and dispersal patterns in the region, and shifting sediment poses safety and efficiency risks to ships in the harbor. With help from the International Atomic Energy Agency, a team of researchers from Kenya and South Africa has deployed a unique system to measure natural radionuclides in beach and aquatic sediments and map sediment transportation in the region. The IAEA described the mission in a photo essay published August 21.

QSA Global, a provider of radioisotope products, and Niowave, a Michigan-based producer of medical radioisotopes, announced that the companies will codevelop a scalable radium purification process using Niowave’s radium-226 processing technology to meet the demand for actinium-225, an alpha-emitter used in the treatment of cancer. According to the companies, the strategic partnership marks a significant advancement in the field of radiopharmaceutical technology, enhancing the supply chain for critical radioisotopes, including Ac-225.

Niowave uses a closed-loop cycle to produce high-purity Ac-225 and other alpha emitters from Ra-226 using a superconducting electron linear accelerator. According to the company’s website, the electron beam impinges on a photon converter to irradiate the Ra-226, inducing a photon-neutron reaction to Ra-225, which decays to Ac-225.

The Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) wants to mimic and accelerate the natural half-life decay chain of alpha-emitting radioisotopes and plans to invite proposals for experimental or theoretical research tracks under Decay on Demand—a new DARPA disruptioneering opportunity. The solicitation was published in draft form on June 27.

International Atomic Energy Agency experts have confirmed that the tritium concentration in the fourth batch of treated water released from Japan’s Fukushima Daiichi nuclear power plant is far below the country’s operational limit.