This paper describes the recent results of divertor simulation research toward the realization of the detached plasma using the end-mirror of a large tandem mirror device. The additional ion cyclotron range of frequency heating in the anchor-cells for higher particle flux generation significantly increases the density, which attained the highest particle flux up to 1.76×1023 particles/s·m2 at the end-mirror exit. Massive gas injection (H2 and noble gases) into the divertor simulation experimental module (D-module) was performed, and a remarkable reduction of the electron temperature on the target plate was successfully achieved associated with the strong reduction of particle and heat fluxes in D-module. Two-dimensional images of Hα emission in D-module observed with a high-speed camera showed strong emission in the upstream region and significant reduction near the target plate. These results clarified the effect of radiation cooling and formation of detached plasma due to gas injection. It is also found that Xe gas is much more effective in achieving detached plasma than Ar gas. Numerical simulation studies also have been performed toward the understanding of the cooling mechanism of divertor plasma. The above results will contribute to establishment of detached plasma control and clarification of the radiation cooling mechanism toward the development of future divertor systems.