A review of corrosion and environmental effects on the mechanical properties of candidate structural alloys for use with liquid metals infusion reactors is presented. The corrosion/mass transfer behavior of austenitic and ferritic steels and vanadium-base alloys is evaluated to determine the preliminary operating temperature limits for circulating and static liquid-lithium and Pb-17Li systems. The influence of liquid-metal environment on the mechanical properties of structural materials is discussed. Corrosion effects of nitrate and fluoride salts are presented. Requirements for additional data are identified.