Fast-neutron dose measurement by the activation of nickel foils involves a correction for thermal-neutron burnup of Co58, the daughter product of the (n,p) reaction. Fast-neutron irradiation of nickel produces Co58 in its ground and excited isomeric states, and recently the isomer has been shown to have a high thermal-neutron-absorption cross section. This paper considers how the determination of fast-neutron dose by nickel activation should be corrected for thermal-neutron burn-up of both ground and isomeric states of Co58. Results, which have been fully corrected, are compared with results obtained at low reactor power where the thermal-neutron burn-up of Co58 and Co58m is negligible. All the data considered were obtained from foils irradiated in rigs in hollow fuel elements in reactors of the DIDO type. The data demonstrate that accurate fast-neutron dose measurements, using nickel activation, in high-flux facilities can only be made if the thermal-neutron cross sections of Co58 and Co58 m and the branching ratio of the Ni58 (n,p) reaction have previously been determined in the neutron spectrum being utilised.