The essential physical phenomena that will occur in Inertial Fusion Energy (IFE) reactors can be studied in a facility where the driver energy and target yield are reduced. The Integrated Test Facility (ITF) will study reactor relevant phenomena affecting drivers, beam transport, targets, and target chambers. The target chambers for reactors and the ITF could be designed using any one of several target chamber concepts. This paper involves the comparison, with computer simulation, of the phenomena occurring in the target chambers of three power reactor concepts (OSIRIS, HYLIFE-II, and CASCADE) with that occurring in ITF target chambers using the same design concept.