A benchmark experiment on tritium breeding in a lithium sphere of 120-cm diameter has been done using the intense 14-MeV neutron source OKTAVIAN at Osaka University. Radial measurement data on 6Li and 7Li tritium production rates and several activation rates inside the lithium sphere agreed with 1-D transport NITRAN and ANISN calculations to within about 20%. For a more detailed comparison, further corrections are thought to be necessary. The anisotropies of intensity and energy on neutron emission with respect to the deuteron beam axis, and scattering effects of source neutrons by the target assembly must be considered.