Magnetic fusion could enable the efficient, large-scale exploration and development of the Solar System. Several conceptual fusion reactor design studies indicate that magnetic fusion may be attractive for space applications—particularly space propulsion. These designs, based on various configurations, share the common characteristics that: (1) the D-3He fuel cycle is used, (2) the plasma provides thrust directly, and (3) continuous, low-thrust trajectories are followed. This paper presents the generic arguments for magnetic fusion power in space, examines fusion fuels and configurations, discusses the trajectories fusion rockets would travel, and explores potential missions.