A breeding blanket design for the tritium production ICF reactor SIRIUS-T is presented. The blanket consists of alternating layers of beryllium multiplier and lithium breeder/coolant with vanadium alloy structure. A tritium breeding ratio of 1.9 can be achieved for the optimum layered configuration with lithium enriched to 90% 6Li. An optimum coolant routing scheme is utilized to achieve adequate thermal hydraulics performance. The maximum structural material temperature is 650°C.