Structural integrity issues are addressed for a symmetric illumination laser driven tritium production facility. At critical locations in the reaction chamber's skeletal frame, mechanical stresses and deflections from self-weight loading are evaluated by finite element methods. Thermal stress analyses of the tiles constituting the chamber's first wall include a comparison of the response of carbon/carbon composite and graphite as well as the influence of irradiation. The results substantiate a viable design for the principal aspects of the reaction chamber.