The results of the safety evaluation of the Blanket Comparison and Selection Study (BCSS) are presented. The safety evaluation measured the relative safety and environmental attractiveness of the final group of BCSS blanket concepts for application with either a tokamak or tandem mirror fusion reactor. Two types of blankets were found to be the most attractive in the safety evaluation. One top-blanket-type is a helium-cooled HT-9 structure with a Li2O breeder, which is preferred if tritium effluent control is good; a lithium breeder would be the backup. The other top blanket concept is liquid-metal-cooled V-15 Cr-5 Ti structure with lithium coolant/breeder, preferred if air and water chemical reactions are adequately controlled; 17Li-83Pb would be the backup coolant/breeder material.