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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Daniel M. Nichols, Michael A. Reichenberger, Andrew D. Maile, Mary R. Holtz, Douglas S. McGregor
Nuclear Science and Engineering | Volume 195 | Number 10 | October 2021 | Pages 1098-1106
Technical Paper | doi.org/10.1080/00295639.2021.1898922
Articles are hosted by Taylor and Francis Online.
The Micro-Pocket Fission Detector (MPFD) is a small-form-factor real-time fission chamber. MPFD performance has been simulated in the Advanced Test Reactor Critical Facility located at Idaho National Laboratory. The neutron and gamma-ray flux profiles and magnitudes were simulated using MCNP in the near-core B-8 irradiation position. These simulations were performed at 69 discrete axial locations inside the B-8 position 55 for three separate orientations of the nearby hafnium outer shim control cylinders and at a power level of 700 W(thermal). The resulting neutron and gamma-ray flux values were used to determine the MPFD response for various fissile masses and detector gas pressures. The optimal gas-operating pressure was determined to be between 30 and 60 psig. The required fissile layer mass was determined to be between 0.5 to 1.0 µg of 235U. Additionally, the gamma ray to fission fragment interaction rate was determined to be 1.43 × 103 with average energy deposition for gamma rays and fission fragments in 30 psig argon gas to be 1 keV and 3.5 MeV, respectively.