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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Jiaxuan Tang, Daogang Lu, Jiangtao Liang, Xiangfeng Ma, Yizhe Liu, Shangshang Ye, Zihan Xia, Yuhao Zhang
Nuclear Science and Engineering | Volume 195 | Number 5 | May 2021 | Pages 478-495
Technical Paper | doi.org/10.1080/00295639.2020.1834314
Articles are hosted by Taylor and Francis Online.
The complex structure of a pool-type sodium-cooled fast reactor may lead to uncertainty and asymmetry of flow and temperature field distributions under a pump stuck accident. This phenomenon has obvious three-dimensional (3-D) thermal-hydraulic characteristics and cannot be analyzed by one-dimensional or two-dimensional models. Previous research has been limited and lacking of 3-D numerical data. Therefore, the commercial computational fluid dynamics software FLUENT is used to simulate a full-scale 3-D integrated model of the China Experimental Fast Reactor (CEFR) in order to obtain 3-D thermal-hydraulic characteristics of key structures and components in the pool-type sodium-cooled fast reactor under a pump stuck accident in the primary loop. The results show that a special asymmetrical backflow phenomenon may occur in the pressure tube and the intermediate heat exchangers (IHXs) of the failure loop under the accident, further leading to complicated flow and thermal characteristics in both the hot and the cold pools. There is obvious thermal stratification and asymmetric temperature distribution, within a temperature difference of more than 90°C between the different loops’ IHX outlet. The temperature difference between the upper and lower areas of the baffles is 20°C to 105°C. This research provides a detailed reference for engineering design and operation.