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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Stefan Meyer, Ivan Otic, Xu Cheng
Nuclear Science and Engineering | Volume 184 | Number 3 | November 2016 | Pages 377-387
Technical Paper | doi.org/10.13182/NSE16-6
Articles are hosted by Taylor and Francis Online.
In the framework of a description of melt pool heat transfer under severe accident conditions, we introduce a computational fluid dynamics approach for the phase change based on the phase-field method. The approach is derived using the formalism of irreversible thermodynamics and depends on a phenomenological expression for the free energy of binary eutectic alloys. The free energy is constructed to describe sharp interfaces on sufficiently small length scales and is capable of representing the appearance of mushy layers in a volume-averaged large-scale perspective. In particular, a dynamic calculation procedure for the diffuse interface width is introduced based on free energy minimization. Numerical simulations using this approach are performed and compared with experimental and numerical results from the literature. These comparisons demonstrate that the new model improves numerical simulation results and is able to describe the dynamics of sharp and diffuse interfaces.