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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Jeremy A. Roberts, Matthew S. Everson, Benoit Forget
Nuclear Science and Engineering | Volume 181 | Number 3 | November 2015 | Pages 331-341
Technical Paper | doi.org/10.13182/NSE14-132
Articles are hosted by Taylor and Francis Online.
A study of the convergence behavior of the eigenvalue response matrix method (ERMM) for nuclear reactor eigenvalue problems is presented. The eigenvalue response matrix equations are traditionally solved by a two-level iterative scheme in which an inner eigenproblem yields particle balance across node boundaries and an outer fixed-point iteration updates the global k-eigenvalue. Past work has shown the method converges rapidly, but the properties of its convergence have not been studied in detail. To perform a formal assessment of these properties, the one-dimensional, one-group diffusion approximation is used to derive the asymptotic error constant of the fixed-point iteration. Several problems are solved numerically, and the observed convergence behavior is compared to the analytic model based on buckling and nodal dimensions (in mean free paths). The results confirm the method converges quickly, with no degradation in the convergence rate for small nodes, which is an observation that suggests ERMM can be used for large-scale, parallel computations with no penalty from the decomposition of a domain into smaller nodes. In addition, results from multigroup problems show that convergence depends strongly on the heterogeneity and the energy representation of a model. In particular, the convergence for two-group and heterogeneous, one-group models is substantially slower than for the homogeneous, one-group model.