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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Liujun Pan, Ruihong Wang, Song Jiang
Nuclear Science and Engineering | Volume 180 | Number 2 | June 2015 | Pages 199-208
Technical Paper | doi.org/10.13182/NSE14-73
Articles are hosted by Taylor and Francis Online.
We propose a modified method to improve the stability of the Monte Carlo fission matrix acceleration (FM) method. In the existing FM method, the weights of fission neutrons are adjusted by the fundamental-mode eigenvector of the fission matrix, which can be calculated by power iteration (PI). In this paper, the PI procedure to calculate the fundamental-mode eigenvector of the fission matrix in each cycle is called the inner iteration to distinguish it from the Monte Carlo iteration cycles. In our proposed method, the fission source distribution tallied during the Monte Carlo simulation is taken as the initial vector for the inner iteration. The weights of the fission neutrons are not adjusted by the fundamental-mode eigenvector of the fission matrix but by the vector obtained with only a few inner iteration steps. We call the proposed method the Monte Carlo fission matrix acceleration method with limited inner iteration (FM_lii). The FM_lii method possesses the following properties: It is more stable than the existing fission matrix acceleration method, and it preserves considerable acceleration efficiency. Moreover, we analyze the stability property of the proposed method for the case of two weakly coupled fissile arrays. A number of numerical tests for practical large-scale, loosely coupled systems are presented that demonstrate the theoretical analysis and efficiency of our scheme.