A comparative study of the efficiency of the hydrophobic catalyst RCTU-3SM in chemical isotope exchange reactions of hydrogen with water and the oxidation of trace amounts of hydrogen in relation to the detritiation tasks of technological streams was carried out. It is shown that, depending on the equilibrium conditions of the isotope exchange process, there is an optimum temperature at which the reaction rate has a maximum. It was found that the rate of oxidation reaction of trace hydrogen depends on the content of oxygen in the purified stream. With oxygen concentration reducing, the oxidation rate initially increases, and when the ratio of oxygen and hydrogen concentrations is less than 100, the rate remains constant within the experimental error.