X-rays size up protein structure at the “heart” of COVID-19 virus

Overlapping X-ray data of the SARS-CoV-2 main protease shows structural differences between the protein at room temperature (orange) and the cryogenically frozen structure (white). Graphic: Jill Hemman/ORNL, U.S. Dept. of Energy

A team of researchers at the Department of Energy’s Oak Ridge and Argonne national laboratories has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease, the enzyme that enables the virus to reproduce.

The X-ray measurements mark an important first step in the researchers’ ultimate goal of building a comprehensive 3D model of the enzymatic protein.

DOE offers $12 million for fusion QIS research

The Department of Energy will provide $12 million for research in quantum information science (QIS) for fusion energy and plasma science. The research is expected to focus on a range of topics, including the design of quantum computing algorithms to solve problems in fusion energy, the development of quantum sensing diagnostics for fusion experiments, and the formation of novel quantum materials using high-energy-density plasmas.

DOE explores cost-sharing program for fusion reactors

The Department of Energy’s Office of Science is inviting input on its plan to develop a cost-share program in fusion reactor technologies. A request for information was published in the Federal Register, inviting interested parties to comment on the topical areas, program objectives, eligibility requirements, program organization and structure, public and private roles and responsibilities, funding modalities, and assessment criteria of such an initiative.