The first of the Generation III+ Advanced Light Water Reactors with advanced digital control rooms are nearing completion or, in some cases, already operational. Compared to their predecessors these control rooms represent a major step change in the display of information. Large panel multiple screen “wall” displays using Keyboard Video Mouse (KVM) networks are the centerpieces of the control rooms of Generation III+ (Gen III+) Nuclear Power Plants. For example, the AP1000 control room wall display consists of 12 wide panel screens. Stations for operators in the control room have four screens. While a very dramatic change for the nuclear industry, other industries have many years of experience operating with these types of displays in operations centers and so called “war rooms”. This paper will outline some of that experience. First experience is reviewed from the oil and gas industry drilling operations, which faces a multitude of complex business challenges. Asset Integrity Management (AIM) using a control center is an overarching approach designed to address these challenges. Experience from the defense industry is then examined. In most cases, a military command and control center’s wall display and KVM routing systems are considered mission critical. They usually provide highly sensitive or very important content to users who are driving key operations and making mission critical decisions. Also examined air traffic control systems and associated training facilities. Finally the experience of a major independent regional electric transmission and distribution organization in building a new 70,000-square-foot Backup Control Center (BCC), some 24 miles from the main control system is described.