The Bowtie methodology is a state-of-the-art qualitative risk management tool that has proven to be extremely useful for the management of major hazard risks in several industry sectors, including oil and gas exploration and production, aviation, transportation, mining, refinery, medical, banking and cybersecurity. Since the methodology is based on the ‘barrier model’ of defense, it is fully compatible with the ‘defense in depth’ approach which is the ´cornerstone´ of the nuclear safety and, therefore, also usable for the management of nuclear power plant safety risks. This paper discusses the benefits that the Bowtie methodology can bring to the process of production of Operational Nuclear Safety Cases to make them accessible and fit-for-purpose documents that can be easily understood at all levels of the licensee organization and used by frontline staff as a tool for the management of day-to-day operational risks. The discussion is facilitated through a sample Bowtie diagram built for a generic Advanced Boiling Water Reactor which depicts the accident scenario associated with High Pressure Core Flooder system line break allowing the ´visualization´ of the whole accident scenario as well as the Bowtie ´benefits´. Finally, the paper includes a brief discussion on the applicability of the Bowtie methodology in the Nuclear Safety Cases for new reactor designs.