A computer program was developed using the MATLAB programming language to simulate the electronics readout for a radiation detector system. The function of each stage of this system is described by a mathematical model in the Laplace domain. The electrical signals have been shown and analyzed at two main outputs of the system. They are described according to their related circuit parameters. The obtained results of the simulation can be used to achieve a best design of the concerned circuits and to provide appropriate details about the system operation. Validation of the simulated signals by comparison with available experimental results has been achieved.