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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Igor A. Bolotnov
Nuclear Technology | Volume 209 | Number 10 | October 2023 | Pages 1405-1413
Review Article | doi.org/10.1080/00295450.2023.2232222
Articles are hosted by Taylor and Francis Online.
The significant progress in the last decade of high-resolution single- and two-phase flow simulations of reactor-relevant flows is summarized in this review paper. The rapid development of high-performance computing capabilities creates exciting opportunities to study complex reactor thermal-hydraulic phenomena. Today’s advances in thermal-hydraulic analysis, interface capturing simulations, and advanced data processing and analysis approaches will help pave the way to the next level of understanding of two-phase flow behavior in nuclear reactors.
This paper discusses two major topics: (1) a brief review of interface-capturing simulations in recent years and (2) several opportunities to advance these numerical research tools in the future. The first part discusses typical computational methods used for these simulations and provides some examples of past work, as well as computational cost estimates and affordability of such simulations for research and industrial applications. In the second part, some specific examples are discussed that could be analyzed using exascale supercomputers being designed and projected to be online in the next several years. New-generation methodologies are required to take full advantage of these capabilities to greatly enhance the scientific understanding of complex two-phase flow phenomena in various conditions relevant to industrial applications.