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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Ivars Neretnieks
Nuclear Technology | Volume 209 | Number 4 | April 2023 | Pages 604-621
Technical Paper | doi.org/10.1080/00295450.2022.2136440
Articles are hosted by Taylor and Francis Online.
Water flows in only a small fraction of the total area of the fractures in fractured rocks. The width of the “channels” is often in the range of centimeters to tens of centimeters. Nuclides can diffuse into and out of the porous rock matrix, which causes them to be significantly retarded compared to the water velocity. In discrete facture networks, diffusion is modeled to be linear and perpendicular to the fracture surface. From a narrow channel, the diffusion cloud would then be as wide as the channel. When the nuclide has propagated farther than the channel width, the diffusion will become essentially radial, which allows the nuclide flux to increase enormously. For the times of interest for a repository for high-level nuclide waste, this will increase nuclide flux into the matrix by tens to thousands of times, and consequently, the nuclide retardation in the flowing water. Radial diffusion was not invoked in the performance assessment of the Forsmark site, which in January 2022 was chosen by the government to locate Sweden’s high-level waste repository. It is shown, using data from this site, that the effect of radial diffusion from the narrow channels considerably increases the retardation of any escaping radionuclides, potentially allowing for the use of thinner copper canisters.