After the Three Mile Island Unit 2 accident, regulatory bodies were concerned about the safety measures in design and operation corresponding to the operator’s decisions and procedures for handling such off-normal transients. Several recommendations were proposed to analyze transients and accidents, improve and revise emergency operating procedures (EOPs), and conduct functional training. In this work, procedural paths were systematically studied to identify the problems in the diagnosis associated with a pilot-operated relief valve (PORV)–break loss-of-coolant accident (LOCA) as well as to suggest new indications for improving the EOPs. Operational parameters during PORV-break LOCA and pipeline-break small-break LOCA were analyzed using a generic pressurized water reactor simulator to compare and justify the symptoms between these two events. It was found that suggesting further indications mainly in the reactor cooling system and containment symptoms may improve the diagnosis of a PORV-break LOCA from the pipeline-break small-break LOCA. This paper presents a practical approach to evaluating diagnostic procedures to better understand operator recovery actions corresponding to reactor system response in dealing with a PORV-break LOCA.