When total volume control is applied to toxicity in nuclear waste management it becomes a limiting factor for the permittable total operating capacity of nuclear reactors. An alternative conceptual scenario is proposed, aimed at toxicity reduction through partitioning and transmutation. Specifically, the electricity generation capacity could be increased by transmutation of 90Sr and 137Cs. Simultaneously, the cooling time before disposal is reduced to 50 years from the 300 years required by existing scenarios, such as the accelerator-driven system. Finally, the scenario is also found to be feasible in terms of energy balance and cost, using an Li(d,xn) reaction neutron source with a deuteron accelerator for transmutation.