Even for small modular reactors (SMRs) with all large pipes removed, a small-break loss-of-coolant accident (SBLOCA) is an important design-basis accident (DBA). Experimental simulation of the SBLOCA scenario is essential before a prototype reactor is realized. The system-integrated modular advanced reactor (SMART) is one of the SMRs developed by the Korea Atomic Energy Research Institute. An integral test loop, SMART-ITL, was also constructed to carry out several types of integral thermal-hydraulic effects tests for the prototype reactor. The SMART-ITL was designed with a preserved height, 1/7th diameter, and 1/49th area, and volume-scaling ratios. Two types of passive safety systems were equipped in the SMART-ITL: a passive safety injection system (PSIS) and a passive residual heat removal system (PRHRS). The PSIS was designed to refill the coolant in the reactor coolant system (RCS) for 72 h after an accident. Under accident conditions the PRHRS prevents overheating and overpressurization of the RCS using two-phase natural circulation. The SBLOCA on the passive safety injection line is a significant DBA that should be validated for differences in break size. In this paper, the effects of two different break sizes, 2 and 7/32 in., were analyzed in order to study the effect of the maximum and minimum mass and energy loss of the RCS. In order to simulate a clear difference between maximum and minimum mass and energy loss of the RCS, heat removal by the PRHRS was performed in the maximum break size (2-in.) accident, and heat removal by the PRHRS was not conducted in the minimum break size (7/32-in.) accident. The difference in mass and energy loss of the RCS will have a significant impact on the operation of the automatic depressurization system. Using the two extreme accident simulations, it was possible to confirm the difference in accident progression caused by the difference in break size and the characteristics of the PSIS.