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Conference Spotlight
Nuclear Energy Conference & Expo (NECX)
September 8–11, 2025
Atlanta, GA|Atlanta Marriott Marquis
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Chris Wagner: The role of Eden Radioisotopes in the future of nuclear medicine
Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.
Svein Sunde, Øivind Berg, Lennart Dahlberg, Nils-Olof Fridqvist
Nuclear Technology | Volume 143 | Number 2 | August 2003 | Pages 103-124
Technical Paper | Nuclear Plant Instrumentation, Control, and Human-Machine Interface Technologies | doi.org/10.13182/NT03-A3401
Articles are hosted by Taylor and Francis Online.
A mathematical model for a boiling water reactor steam-turbine cycle was assembled by means of a configurable, steady-state modeling tool TEMPO. The model was connected to live plant data and intermittently fitted to these by minimization of a weighted least-squares object function. The improvement in precision achieved by this reconciliation was assessed from quantities calculated from the model equations linearized around the minimum and from Monte Carlo simulations. It was found that the inclusion of the flow-passing characteristics of the turbines in the model equations significantly improved the precision as compared to simple mass and energy balances, whereas heat transfer calculations in feedwater heaters did not. Under the assumption of linear model equations, the quality of the fit can also be expressed as a goodness-of-fit Q. Typical values for Q were in the order of 0.9. For a validated model Q may be used as a fault detection indicator, and Q dropped to very low values in known cases of disagreement between the model and the plant state. The sensitivity of Q toward measurement faults is discussed in relation to redundancy. The results of the linearized theory and Monte Carlo simulations differed somewhat, and if a more accurate analysis is required, this is better based on the latter. In practical application of the presently employed techniques, however, assessment of uncertainties in raw data is an important prerequisite.