A study on considerations and strategies for developing safety goals applicable to all nuclear facilities is presented. A scheme of basic safety goals and subsidiary safety goals is assumed, and quantitative basic safety goals for radiation protection of individuals in the vicinity of nuclear facilities are discussed. The risk limit rules are based on comparative risk factors for various health effects, including annual dose, health detriments, acute fatality, latent cancers, and severe hereditary effects. The comparative factor of 1% is used for nonfatal health detriments and 0.1% for fatal effects. A risk limit profile is generated from the risk factors, biological effects, and statistics of injury and mortality rates from general causes. The approaches have potential for developing integrated and comprehensive safety goals.