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First astatine-labeled compound shipped in the U.S.
The Department of Energy’s National Isotope Development Center (NIDC) on March 31 announced the successful long-distance shipment in the United States of a biologically active compound labeled with the medical radioisotope astatine-211 (At-211). Because previous shipments have included only the “bare” isotope, the NIDC has described the development as “unleashing medical innovation.”
Shunsuke Uchida, Masanori Naitoh, Hidetoshi Okada, Hiroaki Suzuki, Soji Koikari, Seiichi Koshizuka, Derek H. Lister
Nuclear Technology | Volume 180 | Number 1 | October 2012 | Pages 65-77
Technical Paper | Thermal Hydraulics | doi.org/10.13182/NT12-A14519
Articles are hosted by Taylor and Francis Online.
A modified six-step evaluation procedure has been proposed to evaluate local wall thinning due to flow-accelerated corrosion (FAC). In step 1, the one-dimensional (1-D) distribution of flow turbulence and the temperature along pipes in cooling systems were analyzed with a 1-D system simulation code to obtain approximate mass transfer coefficients at structure surfaces, prior to using a three-dimensional (3-D) computational fluid dynamics (CFD) code for precise flow turbulence analysis of the major parts. In step 2, corrosive conditions were calculated with a N2H4-O2 reaction analysis code. In step 3, high FAC risk zones were determined for further evaluation for wall thinning rates, based on five parameters: temperature, pH, oxygen concentration, mass transfer coefficient, and chromium content. Then, in step 4, the 3-D CFD code was used to calculate precise mass transfer coefficients at the high FAC risk zones. In step 5, the wall thinning rates were calculated using a coupled model of electrochemical analysis and oxide layer growth analysis by applying the corrosive conditions and the mass transfer coefficients. Finally, in step 6, the residual lifetime of the pipes and the applicability of countermeasures against FAC were evaluated.This paper introduces procedures for determining major FAC parameters and evaluation procedures for high FAC risk zones by synthesizing the parameters in step 3. The procedures for determination of high FAC risk zones in a pressurized water reactor secondary cooling system are also demonstrated.