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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Peiwei Sun, Jin Jiang
Nuclear Technology | Volume 180 | Number 3 | December 2012 | Pages 399-421
Technical Paper | Special Issue on the Initial Release of MCNP6 / Thermal Hydraulics | doi.org/10.13182/NT12-A15352
Articles are hosted by Taylor and Francis Online.
In this paper, a dynamic model of the Canadian supercritical water-cooled reactor (SCWR) is developed to examine its dynamics for potential control system design and analysis. The model development is based on fundamental mass, energy, and momentum conservation equations of major components within the Canadian SCWR operating at supercritical condition. A full set of nonlinear dynamic equations is first derived, from which linearized models are obtained. The linearized models are validated against the full-order nonlinear models in both time domain and frequency domain. The open-loop dynamic characteristics of the Canadian SCWR are investigated through extensive simulations. Steady-state and dynamic couplings among different inputs and outputs are examined using relative gain array and Nyquist plots, and adequate input-output pairings are identified. Cross-coupling at different operating conditions is also evaluated to illustrate the nonlinear behaviors of the system. The developed dynamic model provides a necessary platform for systematic investigation in the control system design and analysis of the Canadian SCWR.