There exists a neutron streaming effect in the high-temperature gas-cooled pebble-bed reactor (HTGR) pebble-bed core caused by the spatial heterogeneity of the neutron’s free path, which has a remarkable impact on neutron leakage. It is necessary to take into consideration the streaming effect in evaluating the homogenized diffusion coefficient of the pebble bed, prior to the whole-core diffusion calculation. In this paper, two methods are proposed for calculating the homogenized multigroup diffusion coefficient of the pebble bed based on migration area conservation theory and Benoist’s theory, respectively. Compared with existing methods, the newly proposed methods are adaptable to a general pebble bed consisting of multitype pebbles and nonvacuum atmosphere. Numerical results demonstrate the proposed methods’ effectiveness and consistency in evaluation of the pebble-bed homogenized diffusion coefficient.