Mass yield distribution has been carried out in the epi-cadmium neutron-induced fission of 241Am by measuring the cumulative yields of fission products within the mass ranges of 80 to 119 and 123 to 161. An off-line gamma-ray spectrometric technique was used for the measurement. From the cumulative yields of the fission products, mass chain yields were obtained by applying the charge distribution correction. From the mass yield distribution, the full-width at tenth-maximum of the light and heavy mass wings, the peak-to-valley (P/V) ratio, the average light mass <AL> and heavy mass <AH>, and the average number of neutrons <ν> were obtained. The mass yield data in the epi-cadmium neutron fission of 241Am were compared with similar data of thermal and 14.8-MeV neutron-induced fission to examine the role of excitation energy on the nuclear structure effect and P/V ratio.