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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Paul K. Romano, Steven P. Hamilton, Ronald O. Rahaman, April Novak, Elia Merzari, Sterling M. Harper, Patrick C. Shriwise, Thomas M. Evans
Nuclear Science and Engineering | Volume 195 | Number 4 | April 2021 | Pages 391-411
Technical Paper | doi.org/10.1080/00295639.2020.1830620
Articles are hosted by Taylor and Francis Online.
While the literature has numerous examples of Monte Carlo (MC) and computational fluid dynamics (CFD) coupling, most are hardwired codes intended primarily for research rather than as stand-alone, general-purpose applications. In this work, we describe an open source application, the Exascale Nuclear Reactor Investigative COde (ENRICO), which enables coupled neutronic and thermal-hydraulic simulations between multiple codes that can be chosen at run time (as opposed to a coupling between two specific codes). The application has been designed such that the control flow logic, domain mapping, nonlinear fixed-point iteration, solution transfers, and convergence checks are all agnostic to the underlying physics solvers used. Special emphasis has also been placed on enabling efficient execution on distributed-memory computing environments. The transfer of solution fields between solvers is performed in memory rather than through filesystem input/output. Additionally, solvers can be configured to run on overlapping or disjoint sets of processes.
To date, coupling with the OpenMC and Shift MC codes, the Nek5000 CFD code, and a simplified heat diffusion and subchannel solver has been implemented in ENRICO. We present results for coupled simulations of a single light water reactor fuel assembly based on the NuScale reactor using various combinations of the physics solvers. For this problem, the coupled simulations are shown to converge in about four Picard iterations. A comparison of the heat source and temperature distributions computed by ENRICO using OpenMC coupled with Nek5000 and Shift coupled with Nek5000 illustrates remarkable agreement between the codes.