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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Taro Ueki
Nuclear Science and Engineering | Volume 195 | Number 2 | February 2021 | Pages 214-226
Technical Paper | doi.org/10.1080/00295639.2020.1801000
Articles are hosted by Taylor and Francis Online.
A dynamical system under extreme physical disorder has the tendency to evolve toward the equilibrium state characterized by an inverse power law power spectrum. In this paper, a practical, implementable, three-dimensional model is proposed for the random media formed by a multimaterials mixture under such a power spectrum using a randomized form of the Weierstrass function, its extension covering the white noise, and partial volume pairings of constituent materials. The proposed model is implemented in the SOLOMON Monte Carlo solver with delta tracking. Two sets of numerical results are shown using the JENDL-4 nuclear data libraries. First, the uncertainty of the neutron effective multiplication factor (keff) due to the inherent uncertainty in the formation of random media is shown for a randomized version of the Bigten core in the International Criticality Safety Benchmark Evaluation Project (ICSBEP). Second, the influence of the exponent of the power spectrum on the uncertainty of keff is evaluated for a randomized version of the Topsy core in the ICSBEP.