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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Dina Chernikova, Imre Pázsit, Andrea Favalli, Stephen Croft
Nuclear Science and Engineering | Volume 185 | Number 1 | January 2017 | Pages 206-216
Technical Paper | doi.org/10.13182/NSE16-47
Articles are hosted by Taylor and Francis Online.
This paper sets up a formalism that is sufficiently general to describe the effects of photofission, photonuclear, (n, xn), (n, n'xγ), and (n, xγ) reactions on the neutron-gamma Feynman-alpha variance-to-mean ratios. Such a formalism is obtained using the Chapman-Kolmogorov (master) forward equation for the above-mentioned set of nuclear reactions. Thereafter, the issue of estimating reaction intensities for gammas in the master equation is highlighted by the paper. As an example, a quantitative evaluation of reaction intensities is given for a case when (n, γ), photonuclear, and (n, 2n) reactions are relevant for the system. However, an evaluation of the influence of these types of reactions to the values of the Feynman variance-to-mean ratios is not within the scope of this paper. Overall, the results obtained in this paper are intended to give an extended systematic framework for the study of the neutron- and gamma-based nondestructive assay problems in nuclear reactor applications and materials control.