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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Tuomas Viitanen, Jaakko Leppänen
Nuclear Science and Engineering | Volume 180 | Number 2 | June 2015 | Pages 209-223
Technical Paper | doi.org/10.13182/NSE14-46
Articles are hosted by Taylor and Francis Online.
This paper discusses the generation of temperature majorant cross sections, the type of cross sections required by two separate techniques related to Monte Carlo neutron tracking, namely, the Doppler-broadening rejection correction (DBRC) and target motion sampling (TMS) temperature treatment methods. In the generation of these cross sections, the theoretically infinite range of thermal motion must be artificially limited by applying some sort of a cutoff condition, which affects both the accuracy and the performance of the calculations. In this paper, a revised approach for limiting thermal motion is first introduced, and then, optimal cutoff conditions are determined for both the traditional majorant, commonly used in DBRC implementations and old implementations of the TMS method, and the revised majorant. Using the revised type of temperature majorant cross sections increases the performance of the TMS method slightly, but no practical difference is observed with the DBRC method. It is also discovered that in ordinary reactor physical calculations, the cutoff conditions originally adopted from the SIGMA1 Doppler-broadening code can be significantly relieved without compromising the accuracy of the results. By updating the cutoff conditions for majorant generation, the CPU time requirement of Serpent 2.1.17 is reduced by 8% to 23% in TMS calculations and by 1% to 6% in problems involving DBRC.