A large cylindrical assembly of 6LiD was irradiated by neutrons from a high-intensity deuterium-tritium source. Small samples of 6Li, 7Li, and 6LiH, all encapsulated in lead, were positioned along the assembly axis and served as indicators for 4He and tritium production. The amount of 4He was determined by isotope dilution mass spectrometry while the tritium content of the 6LiH wafers was measured by proportional counting of gas samples. Careful comparison of the results with TART Monte Carlo calculations showed excellent agreement. For 4He generation, the experimental values were 1.01 ± 0.06 times those of the calculations, while for tritium the ratio was 1.055 ± 0.07.