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Conference Spotlight
Nuclear Energy Conference & Expo (NECX)
September 8–11, 2025
Atlanta, GA|Atlanta Marriott Marquis
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Chris Wagner: The role of Eden Radioisotopes in the future of nuclear medicine
Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.
M. Miguirditchian, D. Guillaneux, N. François, S. Airvault, S. Ducros, D. Thauvin, C. Madic, M. Illemassène, G. Lagarde, J.-C. Krupa
Nuclear Science and Engineering | Volume 153 | Number 3 | July 2006 | Pages 223-232
Technical Paper | doi.org/10.13182/NSE06-A2608
Articles are hosted by Taylor and Francis Online.
The complexation of lanthanide(III) (lanthanum, europium, and lutetium) and americium(III) by four tridentate nitrogen-donor ligands was investigated in homogeneous methanol/water solutions by using structural and thermodynamic approaches. The stoichiometry and inner-sphere hydration state of the europium complexes formed were determined by time-resolved laser-induced fluorimetry. The stability constants and in some cases the thermodynamic parameters were measured by ultraviolet-visible spectrophotometry and the van't Hoff method. The comparison of the stability constant of americium complexes with lanthanide complexes shows better stability for the actinide species. The strong affinity for these ligands toward Am3+ is confirmed by the formation of higher complexes, especially in the case of 2,6-bis-(5,6-dimethyl-1,2,4-triazin-3-yl)-pyridine (MeBTP), the only ligand able to form a 1:3 complex. The influence of the solvent composition on the complexation thermodynamics highlights the effect of the solvent reorganization on the reaction.