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Nuclear Energy Conference & Expo (NECX)
September 8–11, 2025
Atlanta, GA|Atlanta Marriott Marquis
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Chris Wagner: The role of Eden Radioisotopes in the future of nuclear medicine
Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.
J. W. Eerkens
Nuclear Science and Engineering | Volume 150 | Number 1 | May 2005 | Pages 1-26
Technical Paper | doi.org/10.13182/NSE05-A2498
Articles are hosted by Taylor and Francis Online.
Explicit relations are developed to estimate isotope enrichment factors for iQF6 vapors diluted in a carrier gas G, which are isotope selectively laser-excited and flow subsonically through a wall-cooled cylindrical cell. At gas mix pressures below 100 millitorr, laser-assisted condensation repression on cold walls can induce isotope separations for some vapors at certain cryogenic temperatures. For example, for iSF6/N2 mixtures, narrow temperature "windows" are found in the 70 to 90 K region where enrichments exceed i = 33 = 1.7. For iUF6/G gas mixes, enrichment under full condensation conditions is not possible since the surface potential well (~1150 cm-1) of a UF6 condensate layer is higher than the vibration-to-translation conversion quantum of the v3 vibration (~628 cm-1). However, for UF6* adsorptions on a bare surface of F2-passivated gold with well depth of 400 cm-1 or less, initial isotope enrichments with ~ 1.1 are possible before the surface is covered with UF6 condensate. Throughputs in cold-wall isotope separations are low because of low operating pressures. For enrichments of milligrams of a radioactive isotope in nuclear medicine, this is still useful and offers a low-footprint alternative to calutron or ultracentrifuge separations. Since feed and product streams are the same, the method lends itself to multistaging, with one laser irradiating four or more chambers in series.