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Nuclear Energy Conference & Expo (NECX)
September 8–11, 2025
Atlanta, GA|Atlanta Marriott Marquis
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Chris Wagner: The role of Eden Radioisotopes in the future of nuclear medicine
Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.
D. G. Cacuci
Nuclear Science and Engineering | Volume 148 | Number 1 | September 2004 | Pages 55-66
Technical Paper | doi.org/10.13182/NSE148-55
Articles are hosted by Taylor and Francis Online.
This work addresses fundamental aspects of the time- and space-dependent behavior of an Accelerator-Driven Subcritical Core System (ADS) and presents a paradigm ADS neutron kinetics model that is solved exactly. Thus, this paradigm model can serve for benchmarking two- and/or three-dimensional computational tools. Furthermore, this work also proposes a global optimal control theory framework for the operation and control of an ADS. This framework encompasses conceptually the time- and space-dependent behavior of the ADS coupled neutron kinetics/thermal-hydraulic balance equations and aims at the optimal control of ADS operational objectives, which would include minimization of local flux disturbances, load and source following, etc. Importantly, this new conceptual framework makes no use of a "fictitious ADS steady state" and yields the correct and complete (i.e., including sources) adjoint equations, without leaving any room for ambiguities. Thus, this new conceptual framework provides a natural basis for developing new computational methods and corresponding verification experiments specifically tailored for the control and operation of ADS.