This paper describes the procedures for calculating parameters of hydrogen isotopes interaction with materials according to the results of experiments conducted by dynamic sorption methods under conditions of complex exposure. Using the proposed approach, we analyzed the data of reactor tests of a lithium capillary porous system based on a stainless steel matrix conducted under conditions of sample purging with deuterium (at a pressure of deuterium in the chamber ~10–2 to 10–4 Pa). The sample was irradiated at various temperatures (T = 180° to 550°) under conditions of oil-free pumping and with continuous mass spectrometric recording of the gas composition in the chamber.