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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Joseph Dalessio, Eugenio Schuster, David Humphreys, Michael Walker, Yongkyoon In, Jin-Soo Kim
Fusion Science and Technology | Volume 55 | Number 2 | February 2009 | Pages 163-179
Technical Paper | doi.org/10.13182/FST09-A4069
Articles are hosted by Taylor and Francis Online.
In this work, synthesis is employed to stabilize a model of the resistive wall mode (RWM) instability in the DIII-D tokamak. The General Atomics/FAR-TECH DIII-D RWM model, which replaces the spatial perturbation of the plasma with an equivalent perturbation of surface current on a spatially fixed plasma boundary, is used to derive a linear state-space representation of the mode dynamics. The spatial and current perturbations are equivalent in the sense that they both produce the same magnetic field perturbation at surrounding conductors. The key term in the model characterizing the magnitude of the instability is the time-varying uncertain parameter cpp, which is related to the RWM growth rate . Taking advantage of the structure of the state matrices, the model is reformulated into a robust control framework, with the growth rate of the RWM modeled as an uncertain parameter. A robust controller that stabilizes the system for a range of practical growth rates is proposed. The controller is tested through simulations, demonstrating significant performance increase over the classical proportional-derivative controller, extending the RWM growth rate range for which the system is stable and satisfies predefined performance constraints, and increasing the level of tolerable measurement noise. The simulation study shows that the proposed model-based DK controllers can successfully stabilize the mode when the growth rate varies over time during the discharge because of changes in the operating conditions such as pressure and rotation. In terms of robust stability, this method eliminates the need for growth-rate online identification and controller scheduling.Selected Full Papers from15th WORKSHOP ON