One of the key activities on ITER during 2007 is a Design Review covering selected high priority areas of the project in which a significant number of features of the design with the potential to compromise the achievement of some objectives of ITER have been identified. These issues are being addressed by a number of focussed working groups to develop solutions for these issues which will enhance operating margins, reliability and availability, and ensure compliance with the French licensing framework. One of the working groups has been set up to investigate tritium-related issues. The principal design features which are being addressed by this group and the proposed resolutions of these issues are described in the paper.