Large amounts of tritium would be handled in D-T fusion power plants. Tritium is the radioisotope of protium, and is easily taken into the human body. With regard to nuclear fusion reactor facilities, the concept of multi-confinement system is applied to prevent tritium leaking to the environment. The last barrier to confine tritium is a building itself containing all equipment and facilities. If a severe accident takes place, tritium gas could leak into the facilities. In order to prevent tritium leaking to the environment, a secure air cleanup system (ACS) needs to be installed in the building. In ACS, the tritium gas, which leaks to rooms by an accident, is oxidized by catalysts, and then tritiated water vapor is collected by adsorbents. This method can remove tritium effectively, whereas which has a problem related to large ventilation force required to overcome high pressure drop in catalyst and adsorbent beds. Ventilation force could be substantially reduced by applying honeycomb catalysts and adsorbents to ACS. We investigated applicability of honeycomb catalysts and adsorbents to ACS, performing a screening test for the performance of honeycomb catalysts and adsorbents.