The thermionic transient analysis model is used to simulate the startup of the TOPAZ-II space nuclear power system in orbit. The simulated startup procedures are assumed for the purpose of demonstrating the capabilities of the model and may not represent an accurate account of the actual startup procedures of the TOPAZ-II system. The temperature reactivity feedback effects of the moderator, UO2 fuel, electrodes, coolant, and other components in the core are calculated, and their effects on the thermal and criticality conditions of the reactor are investigated. Also, estimates of the time constants of the temperature reactivity feedback for the UO2fuel and the ZrH moderator during startup, as well as of the total temperature reactivity feedback as a function of the reactor steady-state thermal power, are obtained.