Cross sections for the 141Pr(α,x) 144,143,141Pm, 138mPr, 141cum,140cumNd, and 139cumCe reactions were measured by the stacked foil technique at an alpha-particle range of 60 to 20 MeV. Most of the data were obtained for the first time. Experimental data were compared with earlier research and theoretical values from the TENDL-2021 database. Thick target yields of activation products were calculated. The reaction 141Pr(α,5n)140Pm (9.2 s)→140Nd was compared with other 140Nd production routes.