NURETH is the premier international forum for experts in nuclear reactor thermal hydraulics and closely related fields. Held biennially, the conference brings together leading researchers, engineers, and innovators to share cutting-edge developments. NURETH-22 will highlight the latest advancements in thermal-hydraulics, including state-of-the-art computational methods, groundbreaking experimental techniques, new data, innovative analysis methods, and the integration of artificial intelligence and machine learning (AI/ML) into thermal-hydraulic analysis. The conference also fosters global collaboration, encouraging partnerships that drive innovation in these rapidly evolving research areas.