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Conference Spotlight
Nuclear Energy Conference & Expo (NECX)
September 8–11, 2025
Atlanta, GA|Atlanta Marriott Marquis
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The Standards Committee is responsible for the development and maintenance of voluntary consensus standards that address the design, analysis, and operation of components, systems, and facilities related to the application of nuclear science and technology. Find out What’s New, check out the Standards Store, or Get Involved today!
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Chris Wagner: The role of Eden Radioisotopes in the future of nuclear medicine
Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.
Hongbin Zhang (INL), Cole Blakley (Utah State Univ)
Proceedings | 2018 International Congress on Advances in Nuclear Power Plants (ICAPP 2018) | Charlotte, NC, April 8-11, 2018 | Pages 252-261
An approach to uncertainty quantification and sensitivity analysis with coupled simulations of VERACS/ FRAPCON and VERA-CS/BISON was developed within the Multi-Physics Best Estimate Plus Uncertainty (MP-BEPU) safety analysis framework LOTUS. A single assembly model was developed for the VERA-CS simulations and FRAPCON and BISON models were developed for the hot rod in the assembly. Uncertainty quantification and sensitivity analysis were performed with 23 uncertain input parameters for the coupled VERA-CS/FRAPCON simulations and with 31 uncertain input parameters for the coupled VERA-CS/BISON simulations. The maximum fuel centerline temperature (MFCT) and gap conductance at peak power (GCPP) were selected as the figures of merit (FOM). Pearson and Spearman Correlation Coefficients, Sobol Indices and Moment Independent Delta Measures were considered in the sensitivity analysis.
