New neutron production cross sections of tungsten isotopes such as 182W, 183W, 184W, and 186W have been validated through shielding benchmarks and criticality safety benchmarks with the MCNPX-2.5.0 code. The calculation results based on the new evaluations have been compared with those based on ENDF/B-VII.0, JEFF-3.1, JENDL-3.3, and FENDL-2.1 as well as the benchmark experiments. In this paper, some noticeable improvements in calculations of the neutron leakage spectra from tungsten shields and the keff's for critical assemblies with tungsten are presented.