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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Benjamin Wellons, Rishya Sankar Kumaran, Sanghun Lee, Shikha Prasad
Nuclear Technology | Volume 209 | Number 1 | January 2023 | Pages 69-81
Technical Paper | doi.org/10.1080/00295450.2022.2108686
Articles are hosted by Taylor and Francis Online.
An open-source code RadSigPro 1.0 has been developed and used for fast processing of nanosecond-long pulses from scintillation detectors. This processing includes pulse height distribution (PHD), pulse shape discrimination (PSD), and time of flight (TOF). The code has been implemented onto the programmable logic design of a field programmable gate array (FPGA) design for on-the-fly processing of neutron and gamma-ray pulses. A weighted average of the percent difference of the results for RadSigPro 1.0 implemented on a CPU and a FPGA logic design is calculated. This shows a 0% difference for the PHD data sets, a 0.458% and 0.344% difference for the designated gamma detector and neutron detector PSD data sets, respectively, and a 0% difference for the TOF data set. When the FPGA logic design is applied and simulated, it computed the total and tail pulse areas within 5 ns of the arrival of the final data point used for accumulation and also captured the pulse height value within 2 ns of the arrival of the pulse’s maximum data point.